We are committed to the development of successful human medicines. Drugmaking is not a statistical event, nor simply a high-throughput industrialized pursuit. Our team is forging a process for creating and developing novel drug candidates that integrates the most successful drugmaking practices of the past and the best of today's cutting-edge technologies. Our efficient discovery and development processes, focused on important human needs, are generating a robust pipeline.

Our teams are led by proven drug hunters. Ironwood’s integrated, cross-functional teams are led by experienced drug hunters with established records of success discovering, developing, manufacturing, and commercializing marketed drugs with annual sales exceeding $4 billion.

We ask the tough questions early. Ironwood tackles the most difficult aspect of drugmaking: the interface of pharmacology and chemistry. We require our programs to have a pharmacologically validated mechanism along with robust readouts that are predictive of clinical outcomes. This enables Ironwood to rapidly iterate between in vivo models and chemistry to efficiently find lead molecules with clinical promise. Our development teams utilize innovative strategies to evaluate both drug safety and therapeutic proof-of-concept as early as possible. This streamlined approach enables us to effectively prioritize compounds in our portfolio and enhance the likelihood of late phase development success.

We are working together to build an exceptional pharmaceutical company. Each member of our talented team has a clear understanding of his or her role in our drugmaking process. We expect everyone to communicate effectively and to collaborate within and between disciplines. Creating important new medicines is really hard—we take the long view and persevere through the inevitable ups and downs of bringing drugs to patients. We are a committed, passionate group of people working to create drugs that will improve human health.