Senior Scientist / Principal Investigator, Medicinal Chemistry
JOB CODE: AFMC |
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| To apply, send email with a subject of “Job Code AFMC” to careers@ironwoodpharma.com. Please include a CV and cover letter with your email message. |
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| The successful candidate will join the Medicinal Chemistry group to support the identification of high quality drug candidates. The candidate will operate in a hands-on laboratory setting while serving as a key intellectual contributor within: (1) lead identification/optimization efforts within all existing projects and (2) conception/implementation of new projects aimed at enhancing Ironwood?s ever-growing pipeline. |
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- Design, synthesize and characterize molecules as part of Ironwood's lead identification and optimization efforts;
- Evaluate potency, pharmacokinetic and ADME information; develop Structure Activity Relationships based on thorough understanding of drug-like properties;
- Work as part of an integrated team of biologists, pharmacologists, and (bio)analytical and development chemists towards the identification of high quality drug candidates for the advancement into clinical development;
- Participate in the generation and evaluation of new project ideas as part of Ironwood's small molecule pipeline;
- Participate in the development of Ironwood's intellectual property position on various projects;
- Act as an exemplary scientific leader to junior scientists in the Medicinal Chemistry group. |
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- Ph.D. in organic chemistry with 7+ years of relevant industry experience;
- In depth knowledge of synthetic organic and medicinal chemistry;
- Hands-on experience in analytical instrumentation and relevant techniques such as HPLC and NMR;
- Thorough understanding of drug-like properties; working knowledge of the underlying principles of drug metabolism and pharmacokinetics;
- Strong oral and written communication skills. |
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