Media

Beth Calitri

Corporate Communications, Media Relations

978.417.2031

[email protected]

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May 12, 2011

Ironwood Pharmaceuticals Provides First Quarter 2011 Investor Update

May 5, 2011

Ironwood Pharmaceuticals to Host First Quarter 2011 Investor Update Call

May 4, 2011

Ironwood Pharmaceuticals Announces Upcoming Presentation at Bank of America Merrill Lynch 2011 Health Care Conference

March 3, 2011

Ironwood Pharmaceuticals Announces Upcoming Presentation at Cowen and Company Annual Health Care Conference

March 3, 2011

Ironwood Pharmaceuticals Provides Fourth Quarter 2010 Investor Update

February 28, 2011

Ironwood Pharmaceuticals to Host Fourth Quarter 2010 Investor Update Call

January 18, 2011

Ironwood and Protagonist Establish Collaboration for Peptide Drug Discovery and Development

January 6, 2011

Ironwood Pharmaceuticals Announces Upcoming Presentation at J.P. Morgan Healthcare Conference

November 5, 2010

Ironwood Pharmaceuticals Announces Upcoming Presentation at Credit Suisse 2010 Healthcare Conference

November 4, 2010

Ironwood Pharmaceuticals Provides Third Quarter 2010 Investor Update

November 1, 2010

Ironwood and Forest Announce Positive Linaclotide Results from Second Phase 3 Trial in Patients with Irritable Bowel Syndrome with Constipation

November 1, 2010

Ironwood Pharmaceuticals Announces Conference Call to Discuss Positive Linaclotide Phase 3 IBS-C Results

November 1, 2010

Almirall and Ironwood Announce Positive Results from the Second Phase 3 Trial of Linaclotide in Patients with Irritable Bowel Syndrome with Constipation

September 13, 2010

Ironwood and Forest Announce Positive Linaclotide Results from Phase 3 Trial in Patients with Irritable Bowel Syndrome with Constipation

September 13, 2010

Almirall and Ironwood Announce Positive Results from a Phase 3 Trial with Linaclotide in Patients with Irritable Bowel Syndrome with Constipation